Kamagra is typically taken on an as-needed basis, approximately 30 minutes to 1 hour before anticipated sexual activity. It can help men with ED to achieve and maintain an erection when sexually aroused. When a man is sexually aroused, nitric oxide is released in the erectile tissue of the penis. This nitric oxide activates an enzyme called guanylate cyclase, which increases the levels of cyclic guanosine monophosphate (cGMP). cGMP is a molecule that relaxes the smooth muscle cells and dilates the blood vessels in the penis, allowing for increased blood flow.
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